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Default P300 and CMS/DRL
Old 7th March 2018   #1
Join Date: Dec 2017
Posts: 5

I am recording P300 event related potentials with a 32 channel Biosemi Active Two system. Strangely enough I'm seeing an inverted P300 (i.e. negative peaks) at some occipital and temporal electrodes in my data (referencing to average reference does not change this effect). To my understanding this occurs because CMS/DRL were located near to Cz during the recording. Now the CMS/DRL loop tries to compensate the positive voltage caused by a P300 via a negative voltage at DRL. This voltage spreads to more or less neutral electrodes and causes a negative P300. In addition the P300 at central sites is weakened.
My questions are:
Is the above view of things more or less correct or am I missing something? Is there a better position for CMS/DRL for P300?

Please help

I didn't find the right solution from the internet.

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